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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AGL All Species: 22.73
Human Site: S1370 Identified Species: 45.45
UniProt: P35573 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35573 NP_000019.2 1532 174764 S1370 K D S Y G A S S P W C D Y Q L
Chimpanzee Pan troglodytes XP_524777 1532 174746 S1370 K D S Y G A S S P W C D Y Q L
Rhesus Macaque Macaca mulatta XP_001106231 1532 174684 S1370 K D S Y G A S S P W C D Y Q L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_001074795 1532 174269 S1370 K D S Y G A S S P W C D Y Q L
Rat Rattus norvegicus NP_001102034 1532 174314 S1370 K D S Y G A S S P W C D Y Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512323 1163 131293 R1009 P W C D Y Q L R P N F T I A M
Chicken Gallus gallus XP_422317 1532 174660 S1370 K D S Y G A S S P W C D Y Q L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696194 1052 117860 R898 P W C D Y Q L R P N F T I A M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726062 1629 183200 Q1467 T Q S W T D Y Q L R C N F P I
Honey Bee Apis mellifera XP_394961 1549 176545 Q1370 K D S H G A T Q A W A D Y Q L
Nematode Worm Caenorhab. elegans NP_496984 1467 165910 Q1307 T L G F T D F Q L R C N F G I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06625 1536 174953 K1358 R D L Y K S G K P Y E D Y Q L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 97.6 N.A. N.A. 91.9 92.1 N.A. 67.6 81.7 N.A. 53.3 N.A. 45.2 49.9 44.2 N.A.
Protein Similarity: 100 100 99.2 N.A. N.A. 96.6 96.4 N.A. 72 91.5 N.A. 61.3 N.A. 61.4 66.6 62 N.A.
P-Site Identity: 100 100 100 N.A. N.A. 100 100 N.A. 6.6 100 N.A. 6.6 N.A. 13.3 66.6 6.6 N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 100 100 N.A. 13.3 100 N.A. 13.3 N.A. 40 80 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 59 0 0 9 0 9 0 0 17 0 % A
% Cys: 0 0 17 0 0 0 0 0 0 0 67 0 0 0 0 % C
% Asp: 0 67 0 17 0 17 0 0 0 0 0 67 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 9 0 0 0 17 0 17 0 0 % F
% Gly: 0 0 9 0 59 0 9 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 17 % I
% Lys: 59 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 9 9 0 0 0 17 0 17 0 0 0 0 0 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % M
% Asn: 0 0 0 0 0 0 0 0 0 17 0 17 0 0 0 % N
% Pro: 17 0 0 0 0 0 0 0 75 0 0 0 0 9 0 % P
% Gln: 0 9 0 0 0 17 0 25 0 0 0 0 0 67 0 % Q
% Arg: 9 0 0 0 0 0 0 17 0 17 0 0 0 0 0 % R
% Ser: 0 0 67 0 0 9 50 50 0 0 0 0 0 0 0 % S
% Thr: 17 0 0 0 17 0 9 0 0 0 0 17 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 17 0 9 0 0 0 0 0 59 0 0 0 0 0 % W
% Tyr: 0 0 0 59 17 0 9 0 0 9 0 0 67 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _